Thomas Denecker


Researcher in Bioinformatics and Computational Biology, Basketball player, Cook, Photograph

About

Profil

I am a Php student in computational biology and bioinformatics. I'm doing my thesis under the supervision of Gaëlle Lelandais in the BIM team of Institut de Biologie Intégrative de la Cellule (I2BC) directed by Olivier Lespinet. The objective of my thesis is to integrate multiomics data to model iron metabolism in pathogenic yeast species.

Education and Academic Positions


  • 2011 / 2014

    Medical laboratory technician training

    I started with a medical laboratory technician training at Institut de Formation de Techniciens de Laboratoire Médical (IFTLM). During this training, I carried out numerous internships in the hospitals of Paris (APHP)

  • 2014 / 2015

    Bachelor's degree in Bioinformatics

    Feeling a real need in medical laboratories, I continued my studies in Bioinformatics. During this year, I completed 2 internships.

    • "Analyses statistiques de données de cancers" at Institut Jacques Monod (IJM)

    • "Mise en place d'un réseau expérimental autoparamétrable" at Laboratoire Preuves, Programmes et Systèmes - Université Paris Diderot

  • 2015 / 2016

    Master 1 degree in Bioinformatics

    During this year, I completed 2 internships :

    • "Analyses statistiques de données de protéomiques quantitatives chez la levure " at Institut Jacques Monod (IJM)

    • "Analyse de données à haut débit du programme temporel de la réplication " at Institut Jacques Monod (IJM)

  • July 2014

    Master's degree in Bioinformatics

    At Paris Sud - Paris Saclay, I finished my master's degree in the cursus "Biologie Computationnelle : Analyse, Modélisation et Ingénierie de l'Information Biologique et Médicale" (AMI2B). My M2 internships subject was : "Intégration de données génomiques hétérogènes pour la caractérisation des réseaux de régulations transcriptionnelles. Mises en applications dans l’étude du métabolisme du Fer des levures pathogènes. Institut de biologie intégrative de la cellule (I2BC)

  • 2017 / 2020

    PhD student

    I am a Php student in computational biology and bioinformatics. I'm doing my thesis under the supervision of Gaëlle Lelandais in the BIM team of Institut de Biologie Intégrative de la Cellule (I2BC) directed by Olivier Lespinet. The objective of my thesis is to integrate multiomics data to model iron metabolism in pathogenic yeast species.

Publications

Papers


A hypothesis-driven approach identifies CDK4 and CDK6 inhibitors as candidate drugs for treatments of adrenocortical carcinomas.
Djihad Hadjadj, Su-jung Kim, Thomas Denecker, Laura Ben Driss, Jean-Charles Cadoret, Chrystelle Maric, Giuseppe Baldacci and Fabien Fauchereau
Aging (Albany NY). 2017 Dec 26;9(12):2695-2716. doi: 10.18632/aging.101356.

Characterization of the replication timing program of 6 human model cell lines.
Hadjadj D, Denecker T, Maric C, Fauchereau F, Baldacci G, Cadoret JC.
Genom Data. 2016 Jul 15;9:113-7. doi: 10.1016/j.gdata.2016.07.003. eCollection 2016.

Poster


Création d’un outil numérique au service de la communication : application aux bonnes pratiques de lubrification des moteurs chirurgicaux
Chasport C., Coat B., Denecker T., Escalup-Delhommeau R., Chast F.
- SF2S - Antibes (21 et 22 septembre 2017)

Study of the adaptation to iron deficiency of the pathogenic yeast Candida glabrata : bioinformatics analyses of multi-omics data
Denecker T., Poulain P., Zhou Y., Hebert C., Gallopin M., Fairhead C., Bolotin M., Camadro J.M., Angoulvant A. and Lelandais G.
- Junior conference on data science and engineering - Paris Saclay - 14 et 15 septembre 2017

A hypothesis driven approach identifies new targets for treatments of adrenocortical carcinomas
Hadjadj D., Kim SJ., Denecker T., Ben Driss L., Cadoret JC., Maric C., Baldacci G., and Fauchereau F.
- Young Researchers in Life Science – Institut Imagine - Paris (15,16 et 17 mai 2016)

Characterization of the replication timing program in 6 different human cell lines
Hadjadj D, Denecker T, Fauchereau F, Haenni AL, Maric C, Baldacci G, Cadoret JC
- Young Researchers in Life Science – Institut Pasteur - Paris (18,19 et 20 mai 2016)

New method to generate and analyze replication timing in mammalian cells
Hadjadj D., Denecker T., Fauchereau F., Maric C., Haenni AL., Baldacci G., Cadoret JC.
- GDR Replication of eukaryotic chromosomes and its checkpoints - Toulouse (3 et 4 mai 2016)
- Young Researchers in Life Science – Institut Pasteur - Paris (18,19 et 20 mai 2016)